SERS-Active Gold Lace Nanoshells with Built-in Hotspots

Microspectroscopic SERS detection of interleukin-6 with rationally designed gold/silver nanoshells.

Rationally designed gold/silver nanoshells (Au/Ag-NS) with plasmon resonances optimized for red laser excitation in order to minimize autofluorescence from clinical samples exhibit scattering cross-sections, which are ca. one order of magnitude larger compared with solid quasi-spherical gold nanoparticles (Au-NPs) of the same size. Hydrophilic stabilization and sterical accessibility for subseq...

SERS of NIR Active Hollow Gold Nanotags

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SERS-active metal-organic frameworks with embedded gold nanoparticles.

Surface-enhanced Raman scattering (SERS) has been widely used in the detection of targets and strongly depends on the interaction and the distance between the targets and nanoparticles. Herein, metal-organic frameworks (MOFs) were first easily synthesized on a large scale via a water bath method, especially Uio-66 and Uio-67. MOFs embedded with gold nanoparticles (AuNPs) for SERS enhancement we...

Gold Nanoshells in Biomedical Applications

1064 nm SERS of NIR active hollow gold nanotags.

Surface enhanced Raman scattering (SERS) tags are in situ probes that can provide sensitive and selective probes for optical analysis in biological materials. Engineering tags for use in the near infrared (NIR) region is of particular interest since there is an uncongested spectral window for optical analysis due to the low background absorption and scattering from many molecules. An improved s...